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Reverse total shoulder replacement versus anatomical total shoulder replacement for osteoarthritis: population based cohort study using data from the National Joint Registry and Hospital Episode Statistics for England

Objectives To answer a national research priority by comparing the risk-benefit and costs associated with reverse total shoulder replacement (RTSR) and anatomical total shoulder replacement (TSR) in patients having elective primary shoulder replacement for osteoarthritis. Design Population based cohort study using data from the National Joint Registry and Hospital Episode Statistics for England. Setting Public hospitals and publicly funded procedures at private hospitals in England, 2012-20. Participants Adults aged 60 years or older who underwent RTSR or TSR for osteoarthritis with intact rotator cuff tendons. Patients were identified from the National Joint Registry and linked to NHS Hospital Episode Statistics and civil registration mortality data. Propensity score matching and inverse probability of treatment weighting were used to balance the study groups. Main outcome measures The main outcome measure was revision surgery. Secondary outcome measures included serious adverse e

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Clinical Study Team win Crick Translation Prize

A team led by Crick group leader Veni Papayannopoulos and UCLH respiratory consultant Joanna Porter, has been awarded The Crick’s annual Sir David Cooksey Prize in Translation for investigating whether the cystic fibrosis drug Dornase alfa could reduce inflammation in the lungs of COVID-19 patients. Click to read more.

Veni papayannopoulosPauline lukeyVeronique biraultJoel solisPaul nurseJoanna porterDavid roblinCrick translation advisory groupBiomedical research centreResearch officeAntimicrobial defense laboratorySir david cooksey prizeTranslation advisory groupJoint research office

Trends in HIV incidence between 2013–2019 and association of baseline factors with subsequent incident HIV among gay, bisexual, and other men who have sex with men attending sexual health clinics in England: A prospective cohort study

Trends in HIV incidence between 2013–2019 and association of baseline factors with subsequent incident HIV among gay, bisexual, and other men who have sex with men attending sexual health clinics in England: A prospective cohort study
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New era for clinical research in Nottingham

Date Time New era for clinical research in Nottingham A new agreement to create a joint service for the support of clinical researchers in Nottingham is launched today (29 January 2021) by Nottingham University Hospitals NHS Trust and the University of Nottingham. The new Nottingham Joint Research Office (NJRO) promises to significantly improve research and development activity across the two organisations benefiting patients and boosting the city’s world-wide reputation for advances in clinical care. Medical Director for Nottingham University Hospitals NHS Trust, Dr Keith Girling, welcomed the new development and the ambition to bring the existing strengths of both organisations together to deliver greater benefit to patients:

Oxford astrazenecaKeith girlingRuby ali uoKnowledge exchange for university of nottinghamUniversity of nottinghamResearch officeUniversity faculty of medicineNottingham joint research officeNottingham university hospitalsOur joint officeHealth sciencesJoint research officeJoint officeKnowledge exchangeProfessor dame jessica cornerJoint research