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Growing numbers of healthy people are taking dietary supplements but there is little evidence that they protect against non-communicable diseases, say Fang Fang Zhang and colleagues Vitamin and mineral supplements are the most commonly used dietary supplements by populations worldwide.1234 The amount of micronutrients they provide ranges from less than recommended intakes to much more, making them important contributors to total intakes. While supplements can be used to correct micronutrient deficiency or maintain an adequate intake, over-the-counter supplements are most often taken by people with no clinical signs or symptoms of deficiency. However, the effect of vitamin and mineral supplements on the risk of non-communicable diseases in “generally healthy” populations is controversial. We examine patterns of supplement use and the evidence on their effects from randomised trials. Vitamin and mineral supplements have a large worldwide market, but we will focus on their use in N

South koreaUnited kingdomUnited statesFang zhangHelene mcnultyAnna larteySusani barrDariush mozaffarianJeffreyb blumbergNita forouhiWomen health initiative calciumNational healthNutrition examinationUs preventive service task forceNorth americaService task force