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Credit: Garvan Institute of Medical Research
Research led by the Garvan Institute of Medical Research has for the first time mapped the unique genetic profile of the skeleton s master regulator cells, known as osteocytes.
The study published today in
Nature Communications outlines the genes that are switched on or off in osteocytes, a type of bone cell that controls how other types of cells make or break down parts of the skeleton to maintain strong and healthy bones. This new information provides a kind of genetic shortlist we can look to when diagnosing bone diseases that have a genetic component, says the study s first author Dr Scott Youlten, Research Officer in the Bone Biology Lab. Identifying this unique genetic pattern will also help us find new therapies for bone disease and better understand the impacts of current therapies on the skeleton.
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