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VEXAS syndrome in men is more common than previously thought A rare disease first identified in 2020 is much more common than first thought, say researchers at the University of Leeds investigating its origins. VEXAS syndrome is a serious inflammatory condition which develops in men over 50, causing them to become very sick and fatigued, and can be fatal. It was originally thought to be rare, but a new study has identified genetic mutations which indicate that the disease is actually much more common. The researchers developed a genetic test to identify patients who may have the disease, and now want to screen more people showing symptoms to understand exactly how common it is.

United kingdomSinisa savicJames poulterEmily hendersonSchool of medicineEuropean reference networkUniversity of leed school medicineUniversity of leedsClinical associate professorLeed schoolHonorary consultantLeeds teaching hospitalsAcademic fellowMolecular neuroscienceClinical immunologyBone marrow