New technique helps image biological samples at the microscopic level
Researchers have developed a spectroscopic microscope to enable optical measurements of molecular conformations and orientations in biological samples. The novel measurement technique allows researchers to image biological samples at the microscopic level more quickly and accurately.
The new instrument is based on the discrete frequency infrared spectroscopic imaging technique developed by researchers at the Beckman Institute for Advanced Science and Technology at the University of Illinois Urbana-Champaign.
This project is about bringing the study of molecular chirality into the microscopic domain.
Rohit Bhargava, Professor, Bioengineering, Director, Cancer Center, Illinois
Molecular chirality refers to the spatial orientation of atoms in molecules or multimolecule assemblies. In biological systems, one molecule may elicit a cellular response, while its mirror image could be inactive or even toxic. While vib
Researchers at the Beckman Institute have developed a new variation of an infrared microscope with analytical capabilities, rendering it effective for probing the chemical conformations of biomolecules. Their work was published in