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Urine Metabolite Forecasts Diabetic Kidney Failure, Drug Shows Promise

Urine Metabolite Forecasts Diabetic Kidney Failure, Drug Shows Promise
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Metabolite in urine predicts diabetic kidney

High urine levels of adenine, a metabolite produced in the kidney, were associated with a higher risk of kidney failure in three international research cohorts, a team from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported.

First-in-Class Treatment Brings Major Breakthrough for Incurable Kidney Disease

First-in-Class Treatment Brings Major Breakthrough for Incurable Kidney Disease
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Dapagliflozin safe in hospitalized patients with COVID-19 with preserved or reduced kidney function

Washington, DC: In a recent randomized clinical trial of hospitalized patients with COVID-19 and cardio-metabolic risk factors, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin did.

Dapagliflozin did not reduce risks in patients hospitalized with COVID-19

In a recent randomized clinical trial of hospitalized patients with COVID-19 and cardio-metabolic risk factors, the sodium-glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin did not significantly reduce patients' risk of organ failure, kidney problems, or death compared with placebo, although numerically fewer participants treated with dapagliflozin experienced these outcomes. The findings are published in CJASN.

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