Patients who underwent amputation due to a diabetic foot event had a greater risk for early death regardless of the presence or absence of ulcers or gangrene before the amputation.
New research backed up previous findings, showing a substantially higher risk for severe hypocalcemia in older patients on kidney dialysis than in those treated with oral bisphosphonates.
Based on a completed data review, the agency concluded that denosumab increases the risk for severe hypocalcemia in patients with chronic kidney disease.