Common anti-depressant may be first-ever treatment for osteoarthritis
Researchers found that Paroxetine not only slows down cartilage degeneration, but also promotes cartilage health in both mice and human cartilage in vitro.
Image: Fadia Kamal, Penn State
Common anti-depressant may be first-ever treatment for osteoarthritis
Sara LaJeunesse
February 10, 2021
HERSHEY, Pa. A disease of the joints, osteoarthritis affects more than 30 million adults and is the fifth-leading cause of disability in the United States. In a new study, scientists have discovered the cellular pathway that leads to osteoarthritis and have identified a commonly used anti-depressant paroxetine that inhibits this pathway.
The team found that Paroxetine not only slows down cartilage degeneration, but also promotes cartilage health in both mice and human cartilage in vitro. The drug may be the first-ever treatment for this debilitating, degenerative disease.
From Paediatrician to History-sheeter - The Journey of Dr Kafeel Khan
It has taken just three and a half years for this paediatrician to turn into a history-sheeter
Sunday January 31, 2021 11:51 AM, IANS
Gorakhpur (Uttar Pradesh): It has taken just three and a half years for this paediatrician to turn into a history-sheeter .
A suspended paediatrician, seeking his reinstatement at the BRD Medical College, Dr Kafeel Khan has now been declared a history-sheeter which will ensure that he remains under police surveillance.
In a video message on Saturday, Khan said: The situation in UP is such that no surveillance is being done on criminals and a history sheet is being opened against those, including me, who are innocent.