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The first chromosome-level reference genomes of the ornamental banana and pink banana

The genus Musa, encompassing approximately 70 herbaceous species, is predominantly found in the tropical and subtropical regions of Asia and Oceania.

First chromosome-level reference genomes of the ornamental banana and pink banana

Cellular ATP redistribution achieved by deleting Tgparp improves lignocellulose utilization of Trichoderma under heat stress | Biotechnology for Biofuels and Bioproducts

Thermotolerance is widely acknowledged as a pivotal factor for fungal survival across diverse habitats. Heat stress induces a cascade of disruptions in various life processes, especially in the acquisition of carbon sources, while the mechanisms by which filamentous fungi adapt to heat stress and maintain carbon sources are still not fully understood. Using Trichoderma guizhouense, a representative beneficial microorganism for plants, we discover that heat stress severely inhibits the lignocellulases secretion, affecting carbon source utilization efficiency. Proteomic results at different temperatures suggest that proteins involved in the poly ADP-ribosylation pathway (TgPARP and TgADPRase) may play pivotal roles in thermal adaptation and lignocellulose utilization. TgPARP is induced by heat stress, while the deletion of Tgparp significantly improves the lignocellulose utilization capacity and lignocellulases secretion in T. guizhouense. Simultaneously, the absence of Tgparp prevents t

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TSPAN8+ myofibroblastic cancer–associated fibroblasts promote chemoresistance in patients with breast cancer