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RNA inhibitor is shown safe and effective in reducing a wide range of cholesterol and triglyceride levels in the blood

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

France
Roberts-rosenson
Robert-rosenson
Drug-administration
Metabolism-for-the-mount-sinai-health-system
Zodasiran-arrowhead-pharmaceuticals
Icahn-school-of-medicine-at-mount-sinai
European-atherosclerosis-society-congress-on
Mount-sinai
European-atherosclerosis-society-congress
New-england-journal
Arrowhead-pharmaceuticals

Post-hoc Analysis Offers Hope for Novel Cholesterol Drug

Vupanorsen disappointed on triglyceride and non-HDL cholesterol reduction in TRANSLATE-TIMI 70, but post-hoc data on VLDL and remnant cholesterol point to a role for the class if not the drug, experts say.

Milan
Lombardia
Italy
Herlev
Hovedstaden
Denmark
Copenhagen
Køavn
Massachusetts
United-states
Boston
Gentofte

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