Researchers investigated how pre-dementia psychiatric diagnoses relate to well-recognized genetic risk factors for dementia in a large longitudinal population-based cohort the United Kingdom Biobank (UKB).
Predicting the trajectory of neurodevelopmental and psychiatric disorders like autism or schizophrenia is difficult because they can be influenced by many different genetic and environmental factors.
Our genomes provide the instructions for proper growth and development. Millions of genomic switches, known as enhancers, control the location and timing of gene expression, which in turn ensures the correct proteins are made in the right cells at the right time throughout our lives.