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Targeted radiation is often used to study and treat diverse cancer types. A multidisciplinary research team based at the University of Chicago Medicine has recently focused on a type of cell that releases a protein that enhances resistance to cancer therapies and promotes tumor progression.
The study focused on Ter cells, which are extra medullary erythroid precursers that secrete the neuropeptide artemin. In the study, published February 24, 2020, in
Science Translational Medicine, the researchers showed that local tumor radiotherapy, systemic immunotherapy or the combination of both treatments were able to deplete Ter cells in the spleen, reduce artemin production and limit tumor progression both in the locally irradiated tumors as well as outside the radiation fields.
Study shows how some neurons compensate for death of their neighbors eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
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Uterine fibroids are a common cause of heavy menstrual bleeding and pain in women of reproductive age, especially among women of color. An estimated $34 billion in healthcare costs are associated with uterine fibroids in the United States alone each year, yet there are few treatment options other than surgery.
Now a University of Chicago Medicine researcher working with an international team of scientists has developed a daily oral combination therapy that is reliable, safe and effective for long-term treatment of uterine fibroids. This discovery is an important new tool that will be an important addition to the field, said Ayman Al-Hendy, MD, PhD, a professor of obstetrics and gynecology and lead author of the study, which was published February 17, 2021 in the
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Investigators at the University of Chicago Medicine have found that women are less likely to be represented as chairs and reviewers on study sections for the National Institutes of Health (NIH), based on data from one review cycle in 2019. The results, published on Feb. 15 in
JAMA Network Open, have implications for the distribution of federal scientific funding.
The NIH is the top source of federal funding for biomedical research in the U.S., providing critical support and guidance on the nation s research programs. The study sought to understand the gender distribution on NIH study sections, where scientific experts meet several times per year to discuss grant applications and determine what research will receive NIH funding.
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A new study out of the University of Chicago has found that during the initial wave of the COVID-19 outbreak in New York City, only 1 in 5 to 1 in 7 cases of the virus was symptomatic. The research team found that non-symptomatic cases substantially contribute to community transmission, making up at least 50% of the driving force of SARS-CoV-2 infection. The results were published on Feb. 10 in the
When the COVID-19 epidemic arrived in the U.S., the investigators noticed that it was very difficult to estimate what proportion of people infected with SARS-CoV-2 would go on to develop symptoms, partially due to the initial challenges with testing capacity.