AMES, Iowa – The Iowa Soybean Research Center recently awarded funding for four soybean research projects at Iowa State University, the largest level of funding invested in a single year by the ISRC since its inception in 2014.
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GNAS) has previously been associated with overall survival rates (Ang
et al., 2018,
JCO Precis. Oncol. 2:1-18).
The demographics of the patients in the study were 49% men and about 28% early onset patients (age less than 50 at diagnosis). About 80% of the study participants were non-Hispanic whites, with African Americans comprising a larger proportion of early-onset patients (9 of 109 vs. 11 of 276). The somatic variants characteristic of early-onset patients showed significantly higher odds of presenting with nonsilent variations in
PIK3CA,
SMAD3, and
TSC2 (where by nonsilent is meant to include missense, frameshift, nonframeshift, splicing, and nonsense variations that resulted in a change in the primary amino acid sequence of the proteins encoded by these genes). On the other hand, these patients had a 60% decreased odds of having