June 1, 2021 - A new study analyzing the association between an individual's genetics (genotype) and their observable characteristics resulting from the.
Elliot Elson, of Washington University School of Medicine, has been elected to the National Academy of Sciences. Election to the academy is considered one of the highest honors that can be awarded to a U.S. scientist or engineer.
Elliot L. Elson, professor emeritus in the Department of Biochemistry and Molecular Biophysics at Washington University School of Medicine in St. Louis,.
Novel method for identifying biomarkers may aid in early cancer diagnosis
A new University of California, Irvine-led study finds a new method for identifying biomarkers may aid in early cancer diagnosis. The study focused on lung cancer, however the Cell Heterogeneity-Adjusted cLonal Methylation (CHALM) method has been tested on aging and Alzheimer s diseases as well and is expected to be effective for studying other diseases.
We found the CHALM method may be a valuable tool in helping researchers to identify more reliable differentially methylated genes from sequence-based methylation data. For clinicians, this method may aid in cancer diagnosis by helping them identify more useful biomarkers, which are overlooked by the traditional method.
E-Mail
IMAGE: Scatter plots show the correlation between differential expression and differential methylation calculated by the traditional and CHALM methods. view more
Credit: UCI School of Medicine
Irvine, CA - January 27, 2021 - A new University of California, Irvine-led study finds a new method for identifying biomarkers may aid in early cancer diagnosis. The study focused on lung cancer, however the Cell Heterogeneity-Adjusted cLonal Methylation (CHALM) method has been tested on aging and Alzheimer s diseases as well and is expected to be effective for studying other diseases. We found the CHALM method may be a valuable tool in helping researchers to identify more reliable differentially methylated genes from sequence-based methylation data, said Wei Li, PhD, the Grace B. Bell chair and professor of bioinformatics in the Department of Biological Chemistry at the UCI School of Medicine. For clinicians, this method may aid in cancer diagnosis by helping them i