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Video report by ITV News Correspondent Juliet Bremner
Prime Minister Boris Johnson said the deal will help protect jobs and provide certainty to businesses, as he hailed the accomplishment.
European Commission president Ursula von der Leyen said the deal is fair and balanced and it is the right and responsible thing to do for both sides.”
But how have politicians, the leaders of the nations and the people who are most affected by the deal reacted?
Politicians
Labour leader Sir Keir Starmer has said Labour will accept and vote for” the post-Brexit deal when it reaches Parliament, but he said a better deal could have been negotiated.
Sir Keir said: “At a moment of such national significance, it is just not credible for Labour to be on the sidelines.
“That is why I can say today that when this deal comes before Parliament, Labour will accept it and vote for it.
“But let me be absolutely clear – and say directly to the Government – up against no de
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Video report by ITV News Correspondent Juliet Bremner
He s just five years old, but Patrick Patch Dillon could already be a star in the making.
The little boy from Billericay in Essex is - like many of us - wishing for a normal Christmas.
So he created a song to cheer up his friends and raise money for a children s charity which has proved such a hit - it is now in with a chance of being number one.
And the Covid Christmas anthem has already raised thousands of pounds for the Make-A-Wish Foundation.
Here s Patch s song in full: