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SARS-CoV-2: can isolation be limited to those who are truly infectious?

At the height of the COVID-19 pandemic, public health restrictions including self-isolation of positive cases and their close contacts were vital to reduce onward transmission of SARS-CoV-2, thus preventing deaths and the potential overwhelming of health-care services. However, the requirement for prolonged and often repeated episodes of self-isolation has had an enormous impact on individuals psychological, financial, and educational wellbeing, disproportionately affecting those on lower incomes, the self-employed, and those unable to work from home.

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