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Lori Dubuque (Dibble), 59, Plattsburgh | NorthCountryNow

Lori Dubuque (Dibble), 59, Plattsburgh | NorthCountryNow
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Researchers are closer to unraveling the mystery of science behind regeneration

Researchers are closer to unraveling the mystery of science behind regeneration Many salamanders can readily regenerate a lost limb, but adult mammals, including humans, cannot. Why this is the case is a scientific mystery that has fascinated observers of the natural world for thousands of years. Now, a team of scientists led by James Godwin, Ph.D., of the MDI Biological Laboratory in Bar Harbor, Maine, has come a step closer to unraveling that mystery with the discovery of differences in molecular signaling that promote regeneration in the axolotl, a highly regenerative salamander, while blocking it in the adult mouse, which is a mammal with limited regenerative ability.

United statesBar harborMount desert islandHermann hallerSergej nowoshilowJames godwinNadia rosenthalBryan dubuqueKatyae chanEmily hendersonMount desert island biological laboratoryResearch institute of molecular pathologyAustralian regenerative medicine instituteLaboratory in bar harborJackson laboratoryMount desert island biological

MDI Biological Laboratory scientist identifies signaling underlying regeneration

The mystery of why salamanders can regenerate a lost limb, but adult mammals cannot has fascinated observers for thousands of years. Now, a team of scientists led by James Godwin, Ph.D., of the MDI Biological Laboratory in Bar Harbor, Maine, has come a step closer to unraveling that mystery with the discovery of differences in molecular signaling that promote regeneration in the axolotl, a highly regenerative salamander, while blocking it in the adult mouse.

United statesBar harborHermann hallerSergej nowoshilowJames godwinNadia rosenthalBryan dubuqueKatyae chanSciences of the national institutes healthResearch institute of molecular pathologyAustralian regenerative medicine instituteLaboratory in bar harborJackson laboratoryNational instituteInstitutional development award ideSalamander response