for the third, i chose pfizer. there is a lot more data on the homogoulus with israel. same with moderna. the company will have a lot more incentive and access to data for their shot for the third immunization. generally speaking, finish with what you started with is the way i think of this. for the j&j vaccine, it is not a booster, but auto correction. it should have been a two-dose vaccine. it is not protection or immunity waning with the j&j, but it is higher with the two doses. we can talk about some exceptions with the j&j if you are pregnant or on birth control for being at risk for thrombotic issues. should you be looking at a
covid-19 transmission goes up is also going to be interesting to follow. let s talk boosters. will kids need boosters, dr. hotez? most likely yes, because, you know, if you look at the way the antibody responses are going and other factors, t&b cells, to me it looks like both mrna vaccinations were always a three-dose vaccine, and the j&j vaccine was always a two-dose vaccine. in the case of the j&j, it s not really a booster, it s not like the antibody is waning after a single dose, it s staying up, it s just that it was never that high a level in the first place. this is more of an auto correction, it s probably really always been a two-dose vaccine. rochelle walensky talked about this mixing and matching of boosters this morning on the
would expect the fda would move forward on this and then bring it to the centers for disease control, the advisory committee and immunization practices and the cdc director will sign off on it. so i would imagine within a week, m maybe two weeks. with the j&j vaccine, it s a little bit different. it s not so much that immunity is waning or declining, it s that the level of effectiveness is not as high as the two mrna vaccines. it s in the 60 to 70% range, instead of when it was originally released. the 90% range for the mrna vaccines. but it s holding up. it s not really going down. it s just that it probably should have been released as a two-dose vaccine if the very beginning. and so this is really an auto correction in many ways, even though technically they re calling ate booster. let me have you pick up on that. was it a mistake not to have johnson and johnson as a two-shot vaccine? you know, we ve been talking since january, kendis, and from my read, it was always two-dose