/PRNewswire/ The "Single-use Technologies for Biopharmaceuticals: Global Markets" report has been added to ResearchAndMarkets.com s offering. The report.
/PRNewswire/ The "Single-use Technologies for Biopharmaceuticals: Global Markets" report has been added to ResearchAndMarkets.com s offering. The report.
Introduction
Monitoring critical process parameters (CPPs) and key performance indicators in bioreactor control systems is crucial to ensure proper cell growth and protein production. For years, the most important parameters have generally been dissolved oxygen (DO), pH, temperature, and cell concentration. Continual advancement of technology to evaluate these parameters has resulted in faster and more reliable measurements. Additionally, the move to single-use bioreactors (S.U.B.s) for bioproduction has motivated vendors to develop single-use sensors to incorporate into fully single-use workflows.
Recent advances in sensing technologies and a move toward controlling critical quality attributes of a culture have led to the development and use of more advanced sensors. Among the most highly monitored and controlled culture parameters has been cell concentration. However, to monitor cell concentration, the industry has generally relied on off-line measurement methods and analysis bas