announcing on fox news today that he is a "no." the move blindsiding the white house. so what is next for president biden's domestic agenda? here's karen travers. >> reporter: tonight, a potentially fatal blow to president biden's build back better social spending plan. democratic senator joe manchin blindsiding the white house on fox news. >> i cannot vote to continue with this piece of legislation. i just can't. i've tried everything humanly possible. i can't get there. >> you're done? this is a "no." >> this is a "no." >> reporter: the west virginia senator saying he has increasing concerns about the $1.75 trillion price tag and its impact on inflation and the national debt. the white house firing back in a rare, blistering statement aimed at a member of their own party. "senator manchin's comments this morning on fox are at odds with his discussions this week with the president."