and here's one reason why. there are quite extensive mutations on the spike protein, which is an important part of the virus, and the reason that is important is that is the bit which all the vaccines are against, so there is a reasonable chance that at least there will be some degree of vaccine escape with this variant. and the new measures will be reviewed just before christmas. how likely is it that those restrictions could be ratcheted up in three weeks' time, rather than wound down, and can you say with any confidence at the moment that people can keep their christmas plans? i'm pretty confident, or absolutely confident, this christmas will be considerably better than last christmas. but the new measures aren't the entirety of the government's plan b. advice to work from home and vaccine passports in england are still in the back pocket. i was told that boosting the vaccination programme was more important because even if it turns out vaccines are less good at stopping infection from the new variant, they could still offer