WHAT:
In a mouse study, National Institutes of Health researchers have identified and mapped a diverse spectrum of motor neurons along the spinal cord. These neurons, which send and receive messages throughout the body, include a subset that is susceptible to neurodegenerative diseases. Created with a genetic sequencing technique, the atlas reveals 21 subtypes of neurons in discrete areas throughout the spinal cord and offers insight into how these neurons control movement, how they contribute to the functioning of organ systems and why some are disproportionately affected in neurodegenerative diseases.
The study was led by Claire Le Pichon, Ph.D., head of the Unit on the Development of Neurodegeneration at NIH's Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). It appears in