If you know that certain conditions run in your family -- say, high blood pressure or Type 2 diabetes -- you may worry that no matter what you do, you'll end up with the same health woes. Not true. An unhealthy lifestyle is much riskier -- accounting for more than a 78% increased risk of dying prematurely, regardless of genetic predisposition. Genetic predisposition, on the other hand, ups the risk of premature death by just 22% or less (no matter if you have a healthy or unhealthy lifestyle) compared to folks with life-extending genetics.