Mitochondria regulate many processes that are altered in cancer cells, from metabolism to oxidative stress to apoptosis. The metabolic reprogramming in cancer cells promotes an immunosuppressive environment that drives cancer progression. However, in a recent study, researchers from the Salk Institute of Biological Sciences have identified succinate as a metabolite that accumulated due to specific disturbances in the mitochondrial electron transport chain.
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, Salk Institute Of Biological Sciences , Salk Institute , Biological Sciences , Mitochondria , Major Histocompatibility Complex , Mmhc , Salk Institute For Biological Studies ,
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