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February 3, 2021
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This study found that:
Using robotic technology, local levels of opioid metabolites can be measured in wastewater from individual manholes in a sewer system.
Concentrations of nine illicit and prescription opioids, the opioid-agonist treatment drugs methadone and buprenorphine, and the opioid-antagonist overdose reversal drug naloxone in wastewater collected at 10 sites in a North Carolina municipality varied by site.
Wastewater-based epidemiology is a novel approach to study opioid exposure at the community level in order to help public health officials better understand and respond to the current opioid crisis in the United States. In a NIDA-sponsored study, Dr. Noriko Endo and colleagues at Biobot Analytics, Inc., in Somerville, Massachusetts, and from other institutions, used a robotic technology pioneered by one of the study's senior investigators, Dr. Mariana Matus, to sample wastewater from municipal sewers and measure the levels of various opioids. Dr. Peter R. Chai from Brigham and Women’s Hospital, another of the study’s senior investigators, explains that in the past, researchers seeking to directly measure opioid exposure were often limited by the fact that they only had access to people who had some sort of contact with the health care system (e.g., because they suffered an overdose or sought treatment). This made it difficult to obtain accurate data regarding overall opioid use because it excluded information from people who use these drugs and have no interaction with the health care system.

Related Keywords

United States , North Carolina , Massachusetts , Noriko Endo , Peterr Chai , Mariana Matus , Biobot Analytics Inc , Biobot Analytics , Sampling Creates , Wastewater Was Sampled , Selected Manholes , Sampling Site Yielded , Specific Opioid Profile , Med Toxicol , ஒன்றுபட்டது மாநிலங்களில் , வடக்கு கரோலினா , மாசசூசெட்ஸ் , மரியானா மட்டுச் , மாதிரி உருவாக்குகிறது , குறிப்பிட்ட ஓபியாய்டு ப்ரொஃபைல் ,

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