=============================================
On MyHeritage, I have 8 Genetic Groups, all but England centered on the eastern part of the United States:
I filtered my 9,663 DNA matches by "Northeastern and Midwestern USA #6" and saw 3,876 matches. "Northeastern and Midwestern USA #9" had 2,990 matches. "Northeastern and Midwestern USA and Canada (Ontario)" had 3,102 matches.
I'm not sure this is going to help much because of the significant overlap. To me, that's not too helpful!
What about the "England" Genetic Group? It had 2,364 matches. Again, too many to be helpful. Some of my other groups are also in the England group.
I'm sure that this will be helpful for many MyHeritage DNA testers with much smaller genetic groups, but that is not me. All of my Genetic Groups have 20% to 40% of my total matches, most of whom have a tiny or no MyHeritage family tree.