Fecal Microbiome Transplant Not Much Help in Pediatric Obesity

After 6 weeks: aMD -0.021 (95% CI -0.041 to -0.001)
After 12 weeks: aMD -0.023 (95% CI -0.043 to -0.003)
After 26 weeks: aMD -0.029 (95% CI -0.049 to -0.008)
A post-hoc exploratory analysis also found that kids with obesity who fit the criteria for metabolic syndrome at baseline were more likely to have their metabolic syndrome resolved 26 weeks later with FMT compared to the placebo group (adjusted odds ratio 0.06, 95% CI 0.01-0.45,
P=0.007). In total, only four of the 18 participants with metabolic syndrome at baseline still had the condition after their fecal transfer. In contrast, 10 of 13 cases of metabolic syndrome remained in the placebo group.
Those who received the FMT also saw a bit of a shift in community composition as seen via gut microbiome profiling, with this shift maintained for up to 12 weeks after the transfer.

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