ask you, why have doctors been prescribing this? >> well, you know, i think there was enthusiasm in 2008 and there are doctors that will continue to prescribe this because the way medicine works in a population of women, the drug still may have some benefit and cannot say that across the board. the goal as you might say to figure out who will benefit and who's not and we don't know the answer to that so the fda has to look at the aggregate. overall, on the up and up looking at everybody, we think that the benefits do not outweigh the risks, we do not think it increases survival. in europe, as you alluded to, they arrived at a different conclusion. keeping it on the market and used in conjunction with another chemo drug. this is the great uncertainty of medicine sometimes. >> sanjay gupta, i feel for those people suffering from this and just looking for an answer and not getting it. >> they want this sometimes last resort. >> yeah. all right. doctor, thank you. >> thank you. well, it's been a tough week