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The earthquake in mexico. More than 200 people are known to have died in the disaster. Most of the casualties are in mexico city the epicentre of the quake was to the south of the city, in puebla state, approximately 120 kilometres away. The rescue operation continues most urgently at the Enrique Rebsamen Primary School in the south of mexico city. Aleem maqbool tells us what he can see. We have travelled across mexico city and have seen lots of places where there are piles of rubble and soldiers and volunteers trying to find signs of life in those places and we have seen volunteers, regular people with shovels by the side of the road when they hear there might be people trapped, they try to hitch lifts to places to try to help people. But this is where there is the greatest activity, whether Primary School is and it is just a couple of blocks back but this is where there are the most volunteers and soldiers, we have seen rubble being removed but there are lots of people here to support the soldiers and rescue workers with refreshments and rescue workers with refreshments and so on. This really has become the symbol of so much loss because at least 20 children are known to have died, known to have been crushed and thats cool, but there are at least 30 others missing and in the last hour we have heard from rescue workers other might be an entire class full of children with their teachers still trapped inside who might be alive but some rescue workers are saying there are many dead bodies they have also seen inside that they are trying to recover. A very grim scene here in deed but we are seeing scenes like this ina deed but we are seeing scenes like this in a smaller sense in other parts of mexico city and beyond in rural areas where we still do not really know the full impact of the earthquake that happened less than 24 earthquake that happened less than 2a hours ago. Earthquake that happened less than 24 hours ago. Arlene marc bola. This is the second quake to strike in as many weeks and the deadliest in 30 years. Mexico sits at the heart of an earthquake zone, so mexicans know that quakes are likely. So what can be done to minimise the risk of death and destruction that these disasters cause . Heres our science editor, david shukman. The terrifying moment that the quake struck. This is a newsroom in mexico city, wrecked by the tremors. The most violent earthquake in the memory of residents of central mexico. Mexico is all too familiar with this kind of threat. These scenes were filmed in the 19505 and after every tragedy there has been an effort to make buildings tough enough to cope. This was an earthquake that struck in haphazard fashion. But in 1985, another devastating quake tore down 3,000 buildings in mexico city. Killing about 10,000 people. And the government again ordered stricter controls on development. And that did make a difference. When the tremors hit yesterday, this building was among many to shake but not to fall. Using the latest designs to withstand the impact. Sadly, dozens of other places were less resilient. The recent buildings in mexico city should have been built to withstand this kind of shake. It was a magnitude 7 earthquake, but it was some way away from mexico city, and still buildings in mexico city collapsed. So what is behind this earthquake and why does it seem so severe . Countries around the pacific lie on what is called the ring of fire, where the geology is highly active. So mexico has repeatedly suffered from quakes caused yesterday by a violent shift in the rock. The cocos tectonic plate pushing into the north american plate. If we look at a cross section, you can see how one of these plates is actually sliding under the other, moving ata speed of eight centimetres a year, so massive pressures build up, and occasionally there is a sudden rupture. But making things even worse is that much of mexico city has been built on land that is unusually soft, so any tremors from an earthquake are amplified. Mexico city sits in this old lake bed, soft sediments with a lot of water in them, so when the earthquake strikes it, it just goes like jelly. They get really high shaking. A lot of the buildings cannot handle it and they just collapse. So, long before this latest quake, the threat was very well known and for years there has been the technology to keep buildings safe. The problem is making sure the rules are applied, and as rescuers search the school that has collapsed, investigators will want to know what went wrong. Were corners cut in the construction . Is that what led to such terrible losses . David shukman, bbc news. The german election is now only a few days away and one of the topics which has dominated discussion among voters is the countrys migration policy. Two years ago these were the scenes in germany, when more than two Million People arrived in the country during the migrant crisis. Since then the numbers have fallen sharply but many of the migrants remain in germany. One of them was mohammed, who fled from aleppo in syria. Nassim hatam has his story. Piecing together a new life, 16 year old mohammed arrived in germany from syria in 2015, leaving his parents and siblings behind in turkey. Mohammed was taken in by this family, and in two years hes learnt to speak fluent german and is now thinking about his future. Translation well, id like to do something with electronics or machinery when i finish school. Id like to stay in this area. I think its pretty and i think the local people are very nice, and get along with them well. Also, i dont really want to live in a big city, so i think that this place is perfect for me. Mohammeds foster mum christina says taking any refugee child was a big decision. We had in the first moment they really good feeling that he was going to fit in our family, and in this moment we didnt know anything about how hed got to germany, how he got to europe, what the circumstances are, does he still have a family . And what did he see and what did he suffer . Two years ago, i was here in southern germany and witnessed on one weekend alone how thousands of migrants arrived at munich central station. At the time, a lot of germans doubted whether the country would be able to cope. Chancellor merkel said, of course, we can do it, but not everyone agreed. Here in ravensburg, the people took this challenge as an opportunity. As mohammeds story shows, the road to integration begins with learning the language. In this welcome class in a local school, refugee children from nine Different Countries are doing just that. This teacher, an immigrant herself from russia, explained the system to me. Translation you have to imagine that in a year a pupil has to learn as much german as an Elementary School pupil does in four years. After that, he or she has to be able to stay afloat, to learn to find his or her own way, and learn precise technical terms and vocabulary in a specific field. Immigration has been a key theme of this election campaign. Some politicians think that germany has taken on more than it can handle. Translation looking at the labour market, we have a long way to go. 80 of refugees are still unemployed. Changing this will be very difficult, especially given that many of these people dont speak german. Some are even illiterate or lack the qualifications required in our High Performance society. None of this means that we shouldnt help people, but these are problems that do exist and that we will have to deal with for at least the next decade. Back in ravensburg, mohammed, with the support of this family, continues his part in successfully integrating and adapting to a new tune. Nassim hatam, bbc news, ravensburg. You can get more on the top stories on the website. There is continuing coverage on the wrecks the attempts in mexico and details of the path that Hurricane Maria is expected to ta ke that Hurricane Maria is expected to take over the next few days. Myanmars government has defended the speech aung san sui kyi gave on monday about the Rohingya Crisis which Human Rights Group amnesty described as a mix of untruths and victim blaming. Over 400,000 have fled their homes and crossed the border into neighbouring bangladesh. 0ur correspondent, jonah fisher, caught up with dr win myat aye, minister for social welfare, relief and resettlement the man tasked with implementing kofi annans recommendations on rakhine state. The muslim people, not the rohingya, the muslim people. Because many of those who have arrived in bangladesh, more than 400,000 of them, have been saying that they have been driven out by the Burmese Military and that then i put the military and that then i put the military or civilians have been going in and burning their homes . The United Nations human rights commissioner has said the Security Council should consider imposing sanctions on myanmar over its treatment of rohingya muslims, which he calls a textbook case of ethnic cleansing. Zeid Raad Al Hussein has been speaking to our chief international correspondent, lyse doucet, at the un in new york. He says the governments explanation is hard to understand. It is not believable. If they think this is the case, then open up the way for my own people from my office, i have a team, ally was in to ascertain what the facts really are and from what we have established through interviews with those who have fled, and on the basis of satellite images, and our own investigation conducted late last year on which we reported on in january, it seems clear what the sequence is after 55 years of intense oppression, denial of the most basic rights. Inevitably, there was going to be a reaction and we do not support the actions of violent extremists but there was going to be a reaction and this provides a raison detre for what seems to be be wholesale expulsion or at least pa rt be wholesale expulsion or at least part of the rohingya to be moved across to bangladesh. It is so transparent and the habitual denial of the truth is not convincing u nless of the truth is not convincing unless they allow us in so we can support what it is they are saying but they dont. Do you feel helpless . It is maddening. What can be done . The secretary general wrote to the Security Council calling for action and we supported the secretary general and the Security Council came up with a press statement that is the weakest form of expression. We need a resolution which outlines a certain number of things, amongst which there has to be an end to the killing, there are various mechanisms the un can put forward to help with this and there has to be a return of all of those who were expelled back into the state and then if there are no limitations of this, the Security Council should consider other measures. Sanctions . Quite possibly, yes. But we must maintain the pressure because it is not believable. We are hearing what they say in public, defiant and defensive, hardly any sense from them that this is something that can be resolved . Are you talking past each other . We could be, it is fairly obvious that if left unattended were looking at a much broader confrontation than if the Security Council does not assert itself that leaves the space open for more extremist elements to seize control. What do you mean . You have, in essence, our population on the other side which could be subjected to vetting if they are to be allowed backin to vetting if they are to be allowed back in and you can only imagine the frustration if they are not. They are going to become radicalised . Could be. That is what they say, they are linked to extremists . You create a condition which then gives you the excuse to move out the population. It is so transparent and soi population. It is so transparent and so i think to say that they are burning their houses and they are behind this. I do not doubt that some of the rohingya would be joining these groups and we condemn the violence they use. But it is the state that is practising violence wholesale against this essentially defenceless population and it will have deep repercussions for the region, it is fairly obvious. Isnt ita region, it is fairly obvious. Isnt it a measure of our time that it is not just it a measure of our time that it is notjust in this state, look at yemen and syria and south sudan, states are acting with impunity . And for all of the strong words, nothing can be done in our world . The problem is that all of the International System is held together by memory, we created this for a reason and if we forget why we created the system, yes, there is a centrifugal effect acting on the International System and their ability to cope with this and on yemen, for the third year running, i am asking foran yemen, for the third year running, i am asking for an International Investigation, discussions are ongoing in geneva and i hope that nothing short of an International Investigation will be put together because some offal is the situation there and we cannot encrypt conscience allow this to continue. I am waiting to see what happens in geneva. The human rights pressure from the un talking to lyse doucet. For the first time in the uk, scientists have edited the dna of human embryos. The Research Using a technique known as gene editing was performed in laboratories at the Francis Crick institute in london. It is aimed at increasing understanding of the first days of human development. The Scientists Say it might eventually lead to improved ivf treatment. 0ur medical correspondent, fergus walsh, reports. In this lab in central london, scientists are trying to unlock the mysteries of life. How one fertilised cell can go on to create a human. They are doing it by studying the dna of embryos in a dish in theirfirst week. This is basic research that is providing us with a foundation of knowledge about Early Human Development within this first seven day window and our hope is that this information can be used as a basis to build further understanding about underlying causes of infertility. Inside the nucleus of our cells is our genome. Made of dna, its the instruction manual for life. The key sections are genes 20,000 of them, which control how cells function. Scientists at the Crick Institute were targeting a single, super gene called 0ct 4, to see what would happen if it was switched off. This is one of the donated human embryos they used, left over from ivf. You can see that the nucleus of the sperm and the egg havent yet merged to share their dna. They injected the gene editing system known as crisper into each of them. Now the crisper system scans the billions of letters of dna like a spell check, until it gets to the 0ct 4 gene and cuts both strands, removing a tiny section which inactivates or silences the gene. Now we can see what effect tha had. The healthy control on the left shows how an embryo should develop over five days, its getting bigger and eventually developing a cavity at the centre. Now compare that to the gene edited embryo. It keeps collapsing, confirmation thatjust one tiny section of dna is crucial for healthy development. In the long term it could help explain why women like natasha keep losing their pregnancies. Last year alone she had four miscarriages. Its the unknown. We dont know exactly whats going on. To be able to research and find out the crux of what it is, what potentially it could be, could be, just save a lot of heartache. This research was not about creating babies. But in theory, embryo gene editing could one day be used to get rid of inherited disease. That would raise major ethical issues. The aim of this study was basic research. It was to produce knowledge about human development. The embryos that were used in the study were never intended to be implanted. So we should, with respect to this study, put all talk of designer babies off the table. The Crick Institute in london is a world leader in gene editing. A technology which has the potential to transform medicine and our understanding of human biology. Fergus walsh, bbc news. One of sri lankas cricketing greats has called time on his international career. Kumar sangakarra clocked up 100 hundreds and matched brian lara and Sachin Tendulkar as the fastest player to reach 10,000 runs in test cricket. He sat down with my colleague, matthew amroliwala, to reflect on his career. I think as a professional sportsman the desire to compete at the highest level never really disappears, forget the cricketing field, we play a warm up for any competition, even ourfriendly, the a warm up for any competition, even our friendly, the competitive spirit comes out. But my reflection on my game, my reflexes are based on technique and notjust hand eye coordination so i have had the longevity that sometimes players who rely on reflexes may not have. Like isaid rely on reflexes may not have. Like i said before, sometimes you hold on to long and i always think it is better to let go sooner rather than later. You broke into the side at 22, interrupting law studies, did you ever think he would finish equalling brian lara, sutton ten doctor . Reporter at hanging at lords . Not really i remember playing International Cricket was never a prime ambition of mine, mainly because i thought myself never good enough to play for my country. I was playing School Cricket for trinity college, i was 0k. Cricket for trinity college, i was ok. I cricket for trinity college, i was 0k. Idid cricket for trinity college, i was ok. I did not have records that i could boast to the world about. You surprised yourself . Yes, quite a bit and a lot of other people let me ta ke and a lot of other people let me take you back your childhood and the race riots and the civil how much do you remember . Because yourfather hated people from the death squads . 1983, when the race riots were in full swing in colombo and everywhere else in sri lanka, in those days life was less carbonated, that idea of community was very well established in our neighbourhood and ina lot established in our neighbourhood and in a lot of sri lankan homes and communities. We had close to 30 or slightly more friends who are tamil staying with us because it was safer to be with us. To hide . So we ended up to be with us. To hide . So we ended up playing football in the front and cricket and other sports and the games would be interrupted and my pa rents would games would be interrupted and my parents would take everybody in. I did not realise what was going on. I remember going to my father during the riots and saying, i wish this would happen every year because it is great to have all of my friends here be naivety of childhood he told me later on that he did not know how to answer a six year old but he did a couple of years later asi but he did a couple of years later as i grow up. I have heard it said you might return to your law studies, cricket commentary, politics, subsistence farming . What is it likely to be . I dont know, my favourite would be the farming. But in sri lanka there are lots of things that can be done and that i can get involved in. But it has to be something that sits very well with me and my family and my children. How much will you miss it . Terribly, without a doubt. That is a good thing. A lot of players walk away from this game quite bitter and upset and regretting a lot of things that might have been. I walk away with a few regrets, like anyone, but iam not with a few regrets, like anyone, but i am not walking away bitter, i am absolutely happy with the way i played. With what i have achieved. And the game goes on and that is the duty of any sport. It doesnt matter who retires comes into play, the sport will be bigger than all of us. Kumar sangakkara. A recap on the top story. That earthquake in mexico, one and 200 people are known to have died in that disaster, 21 of those children, killed when their Primary School collapsed in the south of mexico city. We will be back at the same time tomorrow. Thank you for watching. Welcome to the longer range forecast we try to give you some detail for the shorter term and pick up on the trends that might affect the country in the coming days. Wednesday was a mishmash of weather conditions and at its best, glorious but if youve got too far towards the north and west, this was the sort of scene that you could have been looking at. It all depended on where you were in relation to this very slow moving weather front, which will take an eternity to work its way across the British Isles during the course of thursday and the fact will not com plete thursday and the fact will not complete its journey until into friday. The best conditions away from that frontal system and into the eastern flank there are still some warmth to be had coming in from the continent. We will talk about that in a second. Anywhere near that front and there is some heavy pulses of rain to be had, it will take match of the day 2 get away from the mainland of scotland and at least brighter skies into the far west and into Northern Ireland and into the far east and the far west later on. Some sunny spells. Round about 20 degrees. That frontal system com pletes degrees. That frontal system completes its journey during the small hours of friday and allow in proceedings, make room for the next set of weather fronts to bring that combination of cloud, wind and rain across scotland, through Northern Ireland will does get one through Northern Ireland through the course of friday and becomes a bother for the western side of england and much of wales. The driest weather towards the east. 0vernight, what is left of the east. 0vernight, what is left of the weather front drifts through and you thinkjust in time for the weekend but look at the number of isobars, cloudy and windy but not quite because is High Pressure over the continent that tends to keep those fronts at bay and not com pletely those fronts at bay and not completely do the job for the western side of scotland and Northern Ireland, seeing some cloud and rain but elsewhere, not a bad start to the weekend and what is left of that front, given it has to run into that area of High Pressure, tending to strangle much of the meister, were left with a band of cloud so not a bad day on we might see some reinvigoration of that front as we get this wave towards the south west, just to finish sunday. Who could be heavy burst of rain and for southern wales. Monday, the main players are there, High Pressure over the continent, keeping these fronts very slow moving. The re m na nts of these fronts very slow moving. The remnants of the front from sunday staggering into the midlands and the north of england and the south west and two other side, warmth in the south and east and fresh and bright across the north and west. Here we go again. Into the forthcoming week, the first half of the week, around midweek, still higher pressure towards the east, low pressure in the atlantic and the jet stream being forced well away from the British Isles so keeping low pressure at bay. Until towards the weekend, we might see the focus of that High Pressure coming towards the south, allowing this door of opportunity to open to the low pressures to flirt with the North Western part of the British Isles, bringing wet and windy weather. Initially, the east west split, some warmth in the south and east for a time when we have the south easterly breezes but there are signs of a breakdown perhaps in the north and west to finish off the week. Goodbye. Tonight at ten, rescue workers in mexico are searching for survivors of an earthquake thats killed at least 200 people. Almost half the confirmed deaths were in the densely populated capital, mexico city, where many buildings have collapsed, and power lines have been cut. The powerful quake, which measured 7. 1 magnitude, struck yesterday afternoon. Many people are still missing. Rescue efforts are still going on in the rubble of a Primary School where 21 children have already been found dead. Translation im desperate. I want them to get the children out. I want to see something. Well have the latest from mexico city and well be looking at the countrys vulnerability to major earthquakes. Also tonight. Mark sampson has been sacked as manager of englands womens Football Team following claims of inappropriate behaviour in a previousjob

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