When it comes to investing, nothing is 100% safe. That's why it's called investing, as opposed to saving — which is basically parking your money in an account so it'll keep its value.
Investing means you're putting money into something — a financial asset of some sort — in the hopes of getting a return. Where there's the chance of a gain, there's always going to be the chance of a loss, too. Risk and reward are two sides of the same investing coin.
That said, not all investments are created equal, risk-wise. Some investments come with extraordinarily low odds that you'll lose your money.