He had been on administrative leave since Feb. 23, said Sandy Valley Local Schools Superintendent David Fischer.
The board accepted his resignation this week.
The alleged sexual conduct with a minor occurred between Jan. 3, 2017, and Jan. 2, 2020.
The alleged victim is not a student in Neading's class and the allegations don't involve his role as a teacher, Stark County Assistant Prosecutor Dan Petricini has told the Canton Repository.
Reach Cassandra Nist at cnist@gannett.com